Hydroxylated Metabolites of the Polybrominated Diphenyl Ether Mixture DE-71 Are Weak Estrogen Receptor-α Ligands | Zendy

Minerva Mercado-Feliciano | Zendy; Robert M. Bigsby | Zendy

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Hydroxylated Metabolites of the Polybrominated Diphenyl Ether Mixture DE-71 Are Weak Estrogen Receptor-α Ligands

Author(s) -

Minerva Mercado-Feliciano,

Robert M. Bigsby

Publication year - 2008

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.11343

Subject(s) - polybrominated diphenyl ethers , metabolite , chemistry , estrogen receptor , microsome , metabolism , endocrine disruptor , estrogen , diphenyl ether , reporter gene , biochemistry , stereochemistry , enzyme , endocrinology , medicine , endocrine system , biology , gene expression , hormone , gene , organic chemistry , cancer , pollutant , breast cancer

Polybrominated diphenyl ethers (PBDEs) are widely found in the environment and are suspected endocrine disruptors. We previously identified six hydroxylated metabolites of PBDE (OH-PBDEs) in treated mice.

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