Open AccessToxicogenomics Data: The Road to Acceptance
Author(s) -
Kris Freeman
Publication year - 2004
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.112-a678
Subject(s) - toxicogenomics , agency (philosophy) , regulatory agency , food and drug administration , regulatory science , medicine , business , toxicology , data science , pharmacology , computer science , political science , sociology , biology , public administration , pathology , social science , biochemistry , gene expression , gene
Regulatory agencies believe microarray data could be extremely useful in testing prospective chemical products and investigating safety problems after chemicals have been marketed. However, it has not yet been clearly established how this information will be used by agencies in the approval of pharmaceuticals and other chemicals--or even whether companies will be required to submit microarray data. Although some private companies are already voluntarily submitting microarray data along with their drug and pesticide applications, others are hesitant to do so. Most of the stakeholders involved agree that standardization of microarray experiment procedures and of genomic signatures are key to the broad acceptance and use of these data.