Interactions between Glutathione S- Transferase P1, Tumor Necrosis Factor, and Traffic-Related Air Pollution for Development of Childhood Allergic Disease | Zendy

Erik Melén | Zendy; Fredrik Nyberg | Zendy; Cecilia M. Lindgren | Zendy; Niklas Berglind | Zendy; Marco Zucchelli | Zendy; Emma Nordling | Zendy; Jenny Hallberg | Zendy; Magnus Svartengren | Zendy; Ralf Morgenstern | Zendy; Juha Kere | Zendy; Tom Bellander | Zendy; Magnus Wickman | Zendy; Göran Pershagen | Zendy

Open Access

Interactions between Glutathione S- Transferase P1, Tumor Necrosis Factor, and Traffic-Related Air Pollution for Development of Childhood Allergic Disease

Author(s) -

Erik Melén,

Fredrik Nyberg,

Cecilia M. Lindgren,

Niklas Berglind,

Marco Zucchelli,

Emma Nordling,

Jenny Hallberg,

Magnus Svartengren,

Ralf Morgenstern,

Juha Kere,

Tom Bellander,

Magnus Wickman,

Göran Pershagen

Publication year - 2008

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.11117

Subject(s) - gstp1 , odds ratio , single nucleotide polymorphism , asthma , medicine , immunology , sensitization , genotype , biology , genetics , gene

Air pollutants may induce airway inflammation and sensitization due to generation of reactive oxygen species. The genetic background to these mechanisms could be important effect modifiers.

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