Global Levels of Histone Modifications in Peripheral Blood Mononuclear Cells of Subjects with Exposure to Nickel | Zendy

Adriana Arita | Zendy; Jingping Niu | Zendy; Qingshan Qu | Zendy; Najuan Zhao | Zendy; Ye Ruan | Zendy; Arthur Nádas | Zendy; Yana Chervona | Zendy; Fen Wu | Zendy; Hong Sun | Zendy; Richard B. Hayes | Zendy; Max Costa | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Global Levels of Histone Modifications in Peripheral Blood Mononuclear Cells of Subjects with Exposure to Nickel

Author(s) -

Adriana Arita,

Jingping Niu,

Qingshan Qu,

Najuan Zhao,

Ye Ruan,

Arthur Nádas,

Yana Chervona,

Fen Wu,

Hong Sun,

Richard B. Hayes,

Max Costa

Publication year - 2011

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1104140

Subject(s) - h3k4me3 , peripheral blood mononuclear cell , histone , population , endocrinology , epigenetics , medicine , chemistry , andrology , in vitro , gene expression , biochemistry , gene , promoter , environmental health

Occupational exposure to nickel (Ni) is associated with an increased risk for lung and nasal cancers. Ni compounds exhibit weak mutagenic activity, cause gene amplification, and disrupt cellular epigenetic homeostasis. However, the Ni-induced changes in global histone modification levels have only been tested in vitro.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research