Bisphenol A and Peripheral Arterial Disease: Results from the NHANES | Zendy

Anoop Shankar | Zendy; Srinivas Teppala | Zendy; Charumathi Sabanayagam | Zendy

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Bisphenol A and Peripheral Arterial Disease: Results from the NHANES

Author(s) -

Anoop Shankar,

Srinivas Teppala,

Charumathi Sabanayagam

Publication year - 2012

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1104114

Subject(s) - medicine , national health and nutrition examination survey , body mass index , odds ratio , risk factor , urinary system , confounding , diabetes mellitus , creatinine , confidence interval , endocrinology , physiology , population , environmental health

Bisphenol A (BPA) is a common chemical used in the manufacture of polycarbonate plastics and epoxy resins, and > 93% of U.S. adults have detectable levels of urinary BPA. Recent animal studies have suggested that BPA exposure may have a role in several mechanisms involved in the development of cardiovascular disease (CVD), including weight gain, insulin resistance, thyroid dysfunction, endothelial dysfunction, and oxidative stress. However, few human studies have examined the association between markers of BPA exposure and CVD. Peripheral arterial disease (PAD) is a subclinical measure of atherosclerotic vascular disease and a strong independent risk factor for CVD and mortality.

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