Open AccessLinking Oxidative Events to Inflammatory and Adaptive Gene Expression Induced by Exposure to an Organic Particulate Matter Component
Author(s) -
Wan-Yun Cheng,
Jenna M. Currier,
Philip A. Bromberg,
Robert Silbajoris,
Steven O. Simmons,
James M. Samet
Publication year - 2011
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1104055
Subject(s) - catalase , heme oxygenase , hmox1 , oxidative stress , chemistry , heme , reactive oxygen species , gene expression , microbiology and biotechnology , biochemistry , biology , enzyme , gene
Toxicological studies have correlated inflammatory effects of diesel exhaust particles (DEP) with its organic constituents, such as the organic electrophile 1,2-naphthoquinone (1,2-NQ).
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