Open AccessIncreased Mitochondrial DNA Copy Number in Occupations Associated with Low-Dose Benzene Exposure
Author(s) -
Michele Carugno,
Angela Cecilia Pesatori,
Laura Dioni,
Mirjam Hoxha,
Valentina Bollati,
Benedetta Albetti,
HyangMin Byun,
Matteo Bonzini,
Silvia Fustii,
Pierluigi Cocco,
Giannina Satta,
Mariagrazia Zucca,
Domenico Franco Merlo,
Massimo Cipolla,
Pier Alberto Bertazzi,
Andrea Baccarelli
Publication year - 2011
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1103979
Subject(s) - mitochondrial dna , medicine , benzene , toxicology , chemistry , biology , genetics , organic chemistry , gene
Benzene is an established leukemogen at high exposure levels. Although low-level benzene exposure is widespread and may induce oxidative damage, no mechanistic biomarkers are available to detect biological dysfunction at low doses.
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