Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential | Zendy

Sumit Gangwal | Zendy; James S. Brown | Zendy; Amy Wang | Zendy; Keith A. Houck | Zendy; David J. Dix | Zendy; Robert J. Kavlock | Zendy; Elaine A. Cohen Hubal | Zendy

Open Access

Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential

Author(s) -

Sumit Gangwal,

James S. Brown,

Amy Wang,

Keith A. Houck,

David J. Dix,

Robert J. Kavlock,

Elaine A. Cohen Hubal

Publication year - 2011

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1103750

Subject(s) - inhalation exposure , nanotoxicology , environmental chemistry , in vitro , nanomaterials , environmental science , occupational exposure , particle (ecology) , chemistry , nanoparticle , nanotechnology , materials science , toxicity , biology , medicine , environmental health , biochemistry , ecology , organic chemistry

Little justification is generally provided for selection of in vitro assay testing concentrations for engineered nanomaterials (ENMs). Selection of concentration levels for hazard evaluation based on real-world exposure scenarios is desirable.

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