Lung Cancer and Cardiovascular Disease Mortality Associated with Ambient Air Pollution and Cigarette Smoke: Shape of the Exposure–Response Relationships | Zendy

C. Arden Pope | Zendy; Richard T. Burnett | Zendy; Michelle C. Turner | Zendy; Aaron Cohen | Zendy; Daniel Krewski | Zendy; Michael Jerrett | Zendy; Susan M. Gapstur | Zendy; Michael J. Thun | Zendy

Open Access

Lung Cancer and Cardiovascular Disease Mortality Associated with Ambient Air Pollution and Cigarette Smoke: Shape of the Exposure–Response Relationships

Author(s) -

C. Arden Pope,

Richard T. Burnett,

Michelle C. Turner,

Aaron Cohen,

Daniel Krewski,

Michael Jerrett,

Susan M. Gapstur,

Michael J. Thun

Publication year - 2011

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1103639

Subject(s) - lung cancer , medicine , environmental health , relative risk , cancer , prospective cohort study , tobacco smoke , cohort study , cohort , disease , confidence interval

Lung cancer and cardiovascular disease (CVD) mortality risks increase with smoking, secondhand smoke (SHS), and exposure to fine particulate matter < 2.5 μm in diameter (PM₂.₅) from ambient air pollution. Recent research indicates that the exposure-response relationship for CVD is nonlinear, with a steep increase in risk at low exposures and flattening out at higher exposures. Comparable estimates of the exposure-response relationship for lung cancer are required for disease burden estimates and related public health policy assessments.

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