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Ambient Particulate Matter Induces Interleukin-8 Expression through an Alternative NF-κB (Nuclear Factor-Kappa B) Mechanism in Human Airway Epithelial Cells
Author(s) -
Robert Silbajoris,
Álvaro Osornio-Vargas,
Steven O. Simmons,
William Reed,
Philip A. Bromberg,
Lisa A. Dailey,
James M. Samet
Publication year - 2011
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1103594
Subject(s) - phosphorylation , chromatin immunoprecipitation , microbiology and biotechnology , western blot , signal transduction , nfkb1 , biology , nf κb , gene expression , transcription factor , chemistry , promoter , biochemistry , gene
Exposure to ambient air particulate matter (PM) has been shown to increase rates of cardiopulmonary morbidity and mortality, but the underlying mechanisms are still not well understood.

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