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Genetic Variation in Base Excision Repair Pathway Genes, Pesticide Exposure, and Prostate Cancer Risk
Author(s) -
Kathryn Hughes Barry,
Stella Koutros,
Sonja I. Berndt,
Gabriella Andreotti,
Jane A. Hoppin,
Dale P. Sandler,
Laurie Burdette,
Meredith Yeager,
Laura E. Beane Freeman,
Jay H. Lubin,
Xiaomei Ma,
Tongzhang Zheng,
Michael C.R. Alavanja
Publication year - 2011
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1103454
Subject(s) - prostate cancer , single nucleotide polymorphism , odds ratio , medicine , genotype , logistic regression , cancer , pesticide , oncology , genetics , biology , bioinformatics , toxicology , gene , agronomy
Previous research indicates increased prostate cancer risk for pesticide applicators and pesticide manufacturing workers. Although underlying mechanisms are unknown, evidence suggests a role of oxidative DNA damage.

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