Arsenic Toxicology: Translating between Experimental Models and Human Pathology | Zendy

J. Christopher States | Zendy; Aaron Barchowsky | Zendy; Iain L. Cartwright | Zendy; John F. Reichard | Zendy; Bernard W. Futscher | Zendy; R. Clark Lantz | Zendy

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Arsenic Toxicology: Translating between Experimental Models and Human Pathology

Author(s) -

J. Christopher States,

Aaron Barchowsky,

Iain L. Cartwright,

John F. Reichard,

Bernard W. Futscher,

R. Clark Lantz

Publication year - 2011

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1103441

Subject(s) - phenotype , epigenetics , biology , disease , human disease , computational biology , gene expression profiling , bioinformatics , genetics , gene , pathology , gene expression , medicine

Chronic arsenic exposure is a worldwide health problem. How arsenic exposure promotes a variety of diseases is poorly understood, and specific relationships between experimental and human exposures are not established. We propose phenotypic anchoring as a means to unify experimental observations and disease outcomes.

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