Region-Specific Growth Effects in the Developing Rat Prostate Following Fetal Exposure to Estrogenic Ultraviolet Filters | Zendy

Luke E. Hofkamp | Zendy; Sarahann Bradley | Zendy; Jesús A.F. Tresguerres | Zendy; W. Lichtensteiger | Zendy; M. Schlumpf | Zendy; Barry G. Timms | Zendy

Open Access

Region-Specific Growth Effects in the Developing Rat Prostate Following Fetal Exposure to Estrogenic Ultraviolet Filters

Author(s) -

Luke E. Hofkamp,

Sarahann Bradley,

Jesús A.F. Tresguerres,

W. Lichtensteiger,

M. Schlumpf,

Barry G. Timms

Publication year - 2008

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.10983

Subject(s) - prostate , developmental toxicity , endocrine system , in vivo , toxicity , no observed adverse effect level , fetus , physiology , biology , teratology , endocrinology , medicine , andrology , toxicology , pregnancy , hormone , cancer , microbiology and biotechnology , genetics

Exposure to environmental endocrine disruptors is a potential risk factor for humans. Many of these chemicals have been shown to exhibit disruption of normal cellular and developmental processes in animal models. Ultraviolet (UV) filters used as sunscreens in cosmetics have previously been shown to exhibit estrogenic activity in in vitro and in vivo assays. We examined the effects of two UV filters, 4-methylbenzylidene camphor (4-MBC) and 3-benzylidene camphor (3-BC), in the developing prostate of the fetal rat.

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