Emergence of Delayed Methylmercury Toxicity after Perinatal Exposure in Metallothionein-Null and Wild-Type C57BL Mice | Zendy

Minoru Yoshida | Zendy; Natsuki Shimizu | Zendy; Megumi Suzuki | Zendy; Chiho Watanabe | Zendy; Masahiko Satoh | Zendy; Kouki Mori | Zendy; Akira Yasutake | Zendy

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Emergence of Delayed Methylmercury Toxicity after Perinatal Exposure in Metallothionein-Null and Wild-Type C57BL Mice

Author(s) -

Minoru Yoshida,

Natsuki Shimizu,

Megumi Suzuki,

Chiho Watanabe,

Masahiko Satoh,

Kouki Mori,

Akira Yasutake

Publication year - 2008

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.10906

Subject(s) - toxicity , methylmercury , offspring , morris water navigation task , physiology , gestation , developmental toxicity , metallothionein , open field , toxicology , pregnancy , endocrinology , medicine , chemistry , biology , biochemistry , environmental chemistry , bioaccumulation , hippocampus , gene , genetics

Although a long latency period of toxicity after exposure to methylmercury (MeHg) is known to exist in humans, few animal studies have addressed this issue. Substantiation of delayed MeHg toxicity in animals would affect the risk evaluation of MeHg.

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