Genetics of Hemostasis: Differential Effects of Heritability and Household Components Influencing Lipid Concentrations and Clotting Factor Levels in 282 Pediatric Stroke Families
Author(s) -
Ulrike NowakGöttl,
Claus Langer,
Sandra Bergs,
Sabine Thedieck,
Ronald Sträter,
Monika Stoll
Publication year - 2008
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.10754
Subject(s) - fibrinogen , antithrombin , heritability , von willebrand factor , medicine , lipoprotein , protein c , endocrinology , protein s , tissue factor pathway inhibitor , hemostasis , coagulation , biology , cholesterol , genetics , tissue factor , heparin , platelet
The identification of heritable and environmental factors possibly influencing a condition at risk should be a prerequisite for the search for the proportion of variance attributable for shared environmental effects (c(2)) modulating the risk of disease. Such epidemiologic approaches in families with a first acute ischemic stroke during early childhood are lacking.
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