Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening | Zendy

Menghang Xia | Zendy; Ruili Huang | Zendy; Kristine L. Witt | Zendy; Noel Southall | Zendy; Jennifer Fostel | Zendy; Ming-Hsuang Cho | Zendy; Ajit Jadhav | Zendy; Cynthia S. Smith | Zendy; James Inglese | Zendy; Christopher J. Portier | Zendy; Raymond R. Tice | Zendy; Christopher P. Austin | Zendy

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Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening

Author(s) -

Menghang Xia,

Ruili Huang,

Kristine L. Witt,

Noel Southall,

Jennifer Fostel,

Ming-Hsuang Cho,

Ajit Jadhav,

Cynthia S. Smith,

James Inglese,

Christopher J. Portier,

Raymond R. Tice,

Christopher P. Austin

Publication year - 2007

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.10727

Subject(s) - cytotoxicity , toxicity , chemical compound , pharmacology , biology , toxicology , computational biology , chemistry , biochemistry , in vitro , organic chemistry

The propensity of compounds to produce adverse health effects in humans is generally evaluated using animal-based test methods. Such methods can be relatively expensive, low-throughput, and associated with pain suffered by the treated animals. In addition, differences in species biology may confound extrapolation to human health effects.

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