Open AccessA Novel Role of the NRF2 Transcription Factor in the Regulation of Arsenite-Mediated Keratin 16 Gene Expression in Human Keratinocytes
Author(s) -
Hitoshi Endo,
Yoshihiko Sugioka,
Yoshihiko Nakagi,
Yasuaki Saijo,
Takahiko Yoshida
Publication year - 2008
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.10696
Subject(s) - hacat , biology , gene expression , transcription factor , regulation of gene expression , nrf1 , activator (genetics) , microbiology and biotechnology , thioredoxin , gene , cell culture , genetics
Inorganic sodium arsenite (iAs) is a ubiquitous environmental contaminant and is associated with an increased risk of skin hyperkeratosis and cancer.
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