Association of Thyroid Hormone Concentrations with Levels of Organochlorine Compounds in Cord Blood of Neonates | Zendy

J. Maervoet | Zendy; Griet Vermeir | Zendy; Adrian Covaci | Zendy; Nicolas Van Larebeke | Zendy; Gudrun Koppen | Zendy; Greet Schoeters | Zendy; Vera Nelen | Zendy; Willy Baeyens | Zendy; Paul Schepens | Zendy; Maria Viaene | Zendy

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Association of Thyroid Hormone Concentrations with Levels of Organochlorine Compounds in Cord Blood of Neonates

Author(s) -

J. Maervoet,

Griet Vermeir,

Adrian Covaci,

Nicolas Van Larebeke,

Gudrun Koppen,

Greet Schoeters,

Vera Nelen,

Willy Baeyens,

Paul Schepens,

Maria Viaene

Publication year - 2007

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.10486

Subject(s) - hormone , thyroid , hexachlorobenzene , medicine , triiodothyronine , endocrinology , cord blood , pollutant , physiology , chemistry , organic chemistry

Thyroid hormones are important regulators of brain development. During critical periods of development, even transient disorders in thyroid hormone availability may lead to profound neurologic impairment. Animal experiments have shown that certain environmental pollutants, including heavy metals and organochlorine compounds such as polychlorinated biphenyls (PCBs) and dioxins, can interfere with thyroid hormone homeostasis. Whether these contaminants can affect circulating levels of thyroid hormones in humans is unclear, however, because the results of available studies are inconsistent.

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