Open AccessHPRT Mutations in Lymphocytes from 1,3-Butadiene-Exposed Workers in China
Author(s) -
Shengxue Liu,
Ao Lin,
Bing Du,
Yanhong Zhou,
Jian gang Yuan,
Yang Bai,
Ziyuan Zhou,
Jia Cao
Publication year - 2007
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.10353
Subject(s) - hypoxanthine guanine phosphoribosyltransferase , exon , carcinogen , microbiology and biotechnology , mutant , mutation , mutation frequency , biology , genetics , gene
1,3-Butadiene (BD) is an important industrial chemical and an environmental and occupational pollutant. The carcinogenicity of BD in rodents has been proved, but its carcinogenic and mutagenic molecular mechanism(s) are not fully elucidated in humans.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom