Cumulative Community-Level Lead Exposure and Pulse Pressure: The Normative Aging Study
Author(s) -
Todd S. Perlstein,
Jennifer Weuve,
Joel Schwartz,
David Sparrow,
Robert E. Wright,
Augusto A. Litonjua,
Huiling Nie,
Howard Hu
Publication year - 2007
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.10350
Subject(s) - pulse pressure , blood pressure , medicine , confidence interval , lead (geology) , pulse wave velocity , cardiology , lead exposure , surgery , endocrinology , biology , paleontology , cats
Pulse pressure increases with age in industrialized societies as a manifestation of arterial stiffening. Lead accumulates in the vasculature and is associated with vascular oxidative stress, which can promote functional and structural vascular disease.
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