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Polymorphisms in Nucleotide Excision Repair Genes, Arsenic Exposure, and Non-Melanoma Skin Cancer in New Hampshire
Author(s) -
Katie M. Applebaum,
Margaret R. Karagas,
David J. Hunter,
Paul J. Catalano,
Steven H. Byler,
Stephen Morris,
Heather H. Nelson
Publication year - 2007
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.10096
Subject(s) - skin cancer , nucleotide excision repair , melanoma , single nucleotide polymorphism , gene , arsenic , biology , genetics , medicine , genotype , cancer research , cancer , dna repair , chemistry , organic chemistry
Arsenic exposure may alter the efficiency of DNA repair. UV damage is specifically repaired by nucleotide excision repair (NER), and common genetic variants in NER may increase risk for non-melanoma skin cancer (NMSC).

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