Characterization of the Impaired Glucose Homeostasis Produced in C57BL/6 Mice by Chronic Exposure to Arsenic and High-Fat Diet | Zendy

David S. Paul | Zendy; Felecia S. Walton | Zendy; R. Jesse Saunders | Zendy; Miroslav Stýblo | Zendy

Open Access

Characterization of the Impaired Glucose Homeostasis Produced in C57BL/6 Mice by Chronic Exposure to Arsenic and High-Fat Diet

Author(s) -

David S. Paul,

Felecia S. Walton,

R. Jesse Saunders,

Miroslav Stýblo

Publication year - 2011

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1003324

Subject(s) - medicine , endocrinology , insulin resistance , diabetes mellitus , impaired glucose tolerance , type 2 diabetes , glucose homeostasis , obesity , homeostasis , insulin , glucose tolerance test

Type 2 diabetes is characterized by glucose intolerance and insulin resistance. Obesity is the leading cause of type 2 diabetes. Growing evidence suggests that chronic exposure to inorganic arsenic (iAs) also produces symptoms consistent with diabetes. Thus, iAs exposure may further increase the risk of diabetes in obese individuals.

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