Open AccessPrenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood
Author(s) -
Stephanie M. Engel,
James G. Wetmur,
Jia Chen,
Chenbo Zhu,
Dana Boyd Barr,
Richard L. Canfield,
Mary S. Wolff
Publication year - 2011
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1003183
Subject(s) - organophosphate , pon1 , paraoxonase , medicine , chlorpyrifos , pregnancy , population , physiology , pediatrics , genotype , environmental health , biology , oxidative stress , pesticide , genetics , gene , agronomy
Prenatal exposure to organophosphate pesticides has been shown to negatively affect child neurobehavioral development. Paraoxonase 1 (PON1) is a key enzyme in the metabolism of organophosphates.
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