Isothiocyanates Reduce Mercury Accumulation via an Nrf2-Dependent Mechanism during Exposure of Mice to Methylmercury | Zendy

Takashi Toyama | Zendy; Yasuhiro Shinkai | Zendy; Akira Yasutake | Zendy; Kôji Uchida | Zendy; Masayuki Yamamoto | Zendy; Yoshito Kumagai | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Isothiocyanates Reduce Mercury Accumulation via an Nrf2-Dependent Mechanism during Exposure of Mice to Methylmercury

Author(s) -

Takashi Toyama,

Yasuhiro Shinkai,

Akira Yasutake,

Kôji Uchida,

Masayuki Yamamoto,

Yoshito Kumagai

Publication year - 2011

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1003123

Subject(s) - chemistry , glutathione , in vivo , neurotoxicity , methylmercury , toxicity , mercury (programming language) , biochemistry , in vitro , pharmacology , microbiology and biotechnology , biology , bioaccumulation , enzyme , environmental chemistry , organic chemistry , computer science , programming language

Methylmercury (MeHg) exhibits neurotoxicity through accumulation in the brain. The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) plays an important role in reducing the cellular accumulation of MeHg.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research