Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease | Zendy

HuiMing Gao | Zendy; Feng Zhang | Zendy; Hui Zhou | Zendy; Wayneho Kam | Zendy; Belinda Wilson | Zendy; JauShyong Hong | Zendy

Open Access

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

Author(s) -

HuiMing Gao,

Feng Zhang,

Hui Zhou,

Wayneho Kam,

Belinda Wilson,

JauShyong Hong

Publication year - 2011

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1003013

Subject(s) - neuroinflammation , neurodegeneration , microglia , dopaminergic , parkinson's disease , oxidative stress , inflammation , neuroprotection , alpha synuclein , neuroscience , dopamine , biology , medicine , pathology , immunology , endocrinology , disease

Mechanisms whereby gene-environment interactions mediate chronic, progressive neurodegenerative processes in Parkinson's disease (PD)-the second most common neurodegenerative disease-remain elusive.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research