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Rotenone, Paraquat, and Parkinson’s Disease
Author(s) -
Caroline M. Tanner,
Freya Kamel,
G. Webster Ross,
Jane A. Hoppin,
Samuel M. Goldman,
Monica Korell,
Connie Marras,
Grace S. Bhudhikanok,
Meike Kasten,
Anabel Chade,
Kathleen Comyns,
Marie Richards,
Cheryl Meng,
Benjamin Priestley,
Hubert H. Fernandez,
Franca Cambi,
David M. Umbach,
Aaron Blair,
Dale P. Sandler,
J. William Langston
Publication year - 2011
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1002839
Subject(s) - rotenone , parkinson's disease , paraquat , medicine , disease , biology , pathology , mitochondrion , biochemistry
Mitochondrial dysfunction and oxidative stress are pathophysiologic mechanisms implicated in experimental models and genetic forms of Parkinson's disease (PD). Certain pesticides may affect these mechanisms, but no pesticide has been definitively associated with PD in humans.

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