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Prolonged Exposure to Particulate Pollution, Genes Associated with Glutathione Pathways, and DNA Methylation in a Cohort of Older Men
Author(s) -
Jaime Madrigano,
Andrea Baccarelli,
Murray A. Mittleman,
Robert O. Wright,
David Sparrow,
Pantel Vokonas,
Letizia Tarantini,
Joel Schwartz
Publication year - 2011
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1002773
Subject(s) - dna methylation , methylation , alu element , biology , dna damage , genotype , gstp1 , genetics , dna , gene , gene expression , human genome , genome
DNA methylation is a potential pathway linking environmental exposures to disease. Exposure to particulate air pollution has been associated with increased cardiovascular morbidity and mortality, and lower blood DNA methylation has been found in processes related to cardiovascular morbidity.

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