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Ambient PM 2.5 Exposure Up-regulates the Expression of Costimulatory Receptors on Circulating Monocytes in Diabetic Individuals
Author(s) -
Alexandra Schneider,
Neil E. Alexis,
David Díaz-Sánchez,
Lucas Neas,
Shirley Harder,
M Herbst,
Wayne E. Cascio,
John B. Buse,
Annette Peters,
Robert B. Devlin
Publication year - 2010
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.1002543
Subject(s) - cd80 , cd86 , immune system , immunology , inflammation , population , flow cytometry , cd40 , receptor , monocyte , medicine , biology , endocrinology , t cell , cytotoxic t cell , in vitro , biochemistry , environmental health
Exposure of humans to air pollutants such as ozone and particulate matter (PM) may result in airway and systemic inflammation and altered immune function. One putative mechanism may be through modification of cell-surface costimulatory molecules.

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