Effects of Short-Term Exposure to Inhalable Particulate Matter on Telomere Length, Telomerase Expression, and Telomerase Methylation in Steel Workers | Zendy

Laura Dioni | Zendy; Mirjam Hoxha | Zendy; Francesco Nordio | Zendy; Matteo Bonzini | Zendy; Letizia Tarantini | Zendy; Benedetta Albetti | Zendy; Alice Savarese | Zendy; Joel Schwartz | Zendy; Pier Alberto Bertazzi | Zendy; Pietro Apostoli | Zendy; Lifang Hou | Zendy; Andrea Baccarelli | Zendy

Open Access

Effects of Short-Term Exposure to Inhalable Particulate Matter on Telomere Length, Telomerase Expression, and Telomerase Methylation in Steel Workers

Author(s) -

Laura Dioni,

Mirjam Hoxha,

Francesco Nordio,

Matteo Bonzini,

Letizia Tarantini,

Benedetta Albetti,

Alice Savarese,

Joel Schwartz,

Pier Alberto Bertazzi,

Pietro Apostoli,

Lifang Hou,

Andrea Baccarelli

Publication year - 2010

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.1002486

Subject(s) - telomerase , telomere , particulates , dna methylation , methylation , biology , toxicology , chemistry , genetics , gene expression , dna , gene , ecology

Shortened leukocyte telomere length (LTL) is a marker of cardiovascular risk that has been recently associated with long-term exposure to ambient particulate matter (PM). However, LTL is increased during acute inflammation and allows for rapid proliferation of inflammatory cells. Whether short-term exposure to proinflammatory exposures such as PM increases LTL has never been evaluated.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research