Hemoglobin, Lead Exposure, and Intelligence Quotient: Effect Modification by the DRD2 Taq IA Polymorphism
Author(s) -
Ananya Roy,
Howard Hu,
David C. Bellinger,
Bhramar Mukherjee,
Rama Modali,
Nasaruddin Khaja,
Joel Schwartz,
Robert O. Wright,
Adrienne S. Ettinger,
Kavitha Palaniapan,
Kalpana Balakrishnan
Publication year - 2010
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0901878
Subject(s) - confidence interval , genotyping , intelligence quotient , confounding , hemoglobin , allele , medicine , genetics , genotype , biology , cognition , psychiatry , gene
Anemia and lead exposure remain significant public health issues in many parts of the world, often occurring together. Animal studies suggest that the dopamine D2 receptor (DRD2) mediates the effects of both lead and iron on cognition and behavior.
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