Bisphenol AF Is a Full Agonist for the Estrogen Receptor ERα but a Highly Specific Antagonist for ERβ
Author(s) -
Ayami Matsushima,
Xiaohui Liu,
Hiroyuki Okada,
Miki Shimohigashi,
Yasuyuki Shimohigashi
Publication year - 2010
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0901819
Subject(s) - estrogen receptor , bisphenol , bisphenol a , agonist , chemistry , receptor , endocrinology , medicine , endocrine disruptor , estrogen receptor alpha , estrogen receptor beta , antagonist , pharmacology , biochemistry , biology , hormone , endocrine system , organic chemistry , cancer , breast cancer , epoxy
Bisphenol AF has been acknowledged to be useful for the production of CF3-containing polymers with improved chemical, thermal, and mechanical properties. Because of the lack of adequate toxicity data, bisphenol AF has been nominated for comprehensive toxicological characterization.
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