Open AccessPhosphorylation of p65 Is Required for Zinc Oxide Nanoparticle–Induced Interleukin 8 Expression in Human Bronchial Epithelial Cells
Author(s) -
Weidong Wu,
James M. Samet,
David B. Peden,
Philip A. Bromberg
Publication year - 2010
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0901635
Subject(s) - chromatin immunoprecipitation , phosphorylation , microbiology and biotechnology , transfection , gene expression , cell culture , reporter gene , a549 cell , messenger rna , chemistry , biology , promoter , gene , biochemistry , genetics
Exposure to zinc oxide (ZnO) in environmental and occupational settings causes acute pulmonary responses through the induction of proinflammatory mediators such as interleukin-8 (IL-8).
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