Particulate Matter–Induced Airway Hyperresponsiveness Is Lymphocyte Dependent | Zendy

Vanessa Saunders | Zendy; Patrick N. Breysse | Zendy; Jennifer Clark | Zendy; Alyssa Sproles | Zendy; Melissa D. Davila | Zendy; Marsha WillsKarp | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Particulate Matter–Induced Airway Hyperresponsiveness Is Lymphocyte Dependent

Author(s) -

Vanessa Saunders,

Patrick N. Breysse,

Jennifer Clark,

Alyssa Sproles,

Melissa D. Davila,

Marsha WillsKarp

Publication year - 2010

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.0901461

Subject(s) - bronchoalveolar lavage , immunology , cytokine , inflammation , lymphocyte , bronchial hyperresponsiveness , biology , medicine , lung , respiratory disease

Exposure to airborne particulate matter (PM), a major component of air pollution, has been associated with increases in both exacerbations of and hospitalizations for asthma. We have previously shown that exposure to ambient PM collected in urban Baltimore (AUB) induces airway hyperresponsiveness (AHR), eosinophilic and neutrophilic inflammation, and the recruitment of T cells. However, the mechanism(s) by which it induces these features of asthma remains unknown.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research