Black Carbon Exposures, Blood Pressure, and Interactions with Single Nucleotide Polymorphisms in MicroRNA Processing Genes
Author(s) -
Elissa H. Wilker,
Andrea Baccarelli,
Helen Suh,
Pantel Vokonas,
Robert O. Wright,
Joel Schwartz
Publication year - 2010
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0901440
Subject(s) - single nucleotide polymorphism , snp , microrna , confounding , blood pressure , medicine , genetics , bioinformatics , gene , biology , genotype
Black carbon (BC) is a marker of traffic pollution that has been associated with blood pressure (BP), but findings have been inconsistent. MicroRNAs (miRNAs) are emerging as key regulators of gene expression, but whether polymorphisms in genes involved in processing of miRNAs to maturity influence susceptibility to BC has not been elucidated.
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