In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project | Zendy

Richard Judson | Zendy; Keith A. Houck | Zendy; Robert J. Kavlock | Zendy; Thomas B. Knudsen | Zendy; Matthew T. Martin | Zendy; Holly M. Mortensen | Zendy; David M. Reif | Zendy; Daniel M. Rotroff | Zendy; Imran Shah | Zendy; Ann M. Richard | Zendy; David J. Dix | Zendy

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In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

Author(s) -

Richard Judson,

Keith A. Houck,

Robert J. Kavlock,

Thomas B. Knudsen,

Matthew T. Martin,

Holly M. Mortensen,

David M. Reif,

Daniel M. Rotroff,

Imran Shah,

Ann M. Richard,

David J. Dix

Publication year - 2009

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.0901392

Subject(s) - in vitro toxicology , in silico , toxicity , computational biology , biology , in vivo , prioritization , xenobiotic , environmental toxicology , toxicant , chemical compound , in vitro , pharmacology , toxicology , microbiology and biotechnology , chemistry , genetics , biochemistry , enzyme , gene , organic chemistry , management science , economics

Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use, and the thousands of environmental chemicals lacking toxicity data. The U.S. Environmental Protection Agency's ToxCast program aims to address these concerns by screening and prioritizing chemicals for potential human toxicity using in vitro assays and in silico approaches.

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