Exposure to Metal-Rich Particulate Matter Modifies the Expression of Candidate MicroRNAs in Peripheral Blood Leukocytes | Zendy

Valentina Bollati | Zendy; Barbara Marinelli | Zendy; Pietro Apostoli | Zendy; Matteo Bonzini | Zendy; Francesco Nordio | Zendy; Mirjam Hoxha | Zendy; V. Pégoraro | Zendy; Valeria Motta | Zendy; Letizia Tarantini | Zendy; Laura Cantone | Zendy; Joel Schwartz | Zendy; Pier Alberto Bertazzi | Zendy; Andrea Baccarelli | Zendy

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Exposure to Metal-Rich Particulate Matter Modifies the Expression of Candidate MicroRNAs in Peripheral Blood Leukocytes

Author(s) -

Valentina Bollati,

Barbara Marinelli,

Pietro Apostoli,

Matteo Bonzini,

Francesco Nordio,

Mirjam Hoxha,

V. Pégoraro,

Valeria Motta,

Letizia Tarantini,

Laura Cantone,

Joel Schwartz,

Pier Alberto Bertazzi,

Andrea Baccarelli

Publication year - 2010

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.0901300

Subject(s) - microrna , gene expression , oxidative stress , particulates , aerodynamic diameter , biology , microbiology and biotechnology , gene , real time polymerase chain reaction , andrology , immunology , chemistry , toxicology , medicine , endocrinology , genetics , ecology

Altered patterns of gene expression mediate the effects of particulate matter (PM) on human health, but mechanisms through which PM modifies gene expression are largely undetermined. MicroRNAs (miRNAs) are highly conserved, noncoding small RNAs that regulate the expression of broad gene networks at the posttranscriptional level.

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