Open AccessMaternal Dioxin Exposure Combined with a Diet High in Fat Increases Mammary Cancer Incidence in Mice
Author(s) -
Michele A. La Merrill,
Rachel Harper,
Linda S. Birnbaum,
Robert D. Cardiff,
David W. Threadgill
Publication year - 2009
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0901047
Subject(s) - offspring , endocrinology , medicine , mammary gland , breast cancer , lactation , biology , cyp1b1 , weaning , cancer , physiology , pregnancy , cytochrome p450 , metabolism , genetics
RESULTS from previous studies have suggested that breast cancer risk correlates with total lifetime exposure to estrogens and that early-life 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure or diets high in fat can also increase cancer risk.
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