Open AccessLow-Dose Arsenic Compromises the Immune Response to Influenza A Infection in Vivo
Author(s) -
Courtney D. Kozul,
Kenneth H. Ely,
Richard I. Enelow,
Joshua W. Hamilton
Publication year - 2009
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0900911
Subject(s) - immune system , immunology , influenza a virus , virus , medicine , lung , bronchiectasis , biology
Arsenic exposure is a significant worldwide environmental health concern. We recently reported that 5-week exposure to environmentally relevant levels (10 and 100 ppb) of As in drinking water significantly altered components of the innate immune response in mouse lung, which we hypothesize is an important contributor to the increased risk of lung disease in exposed human populations.
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