Malondialdehyde–Deoxyguanosine Adducts among Workers of a Thai Industrial Estate and Nearby Residents
Author(s) -
Marco Peluso,
Petcharin Srivatanakul,
Armelle Munnia,
Adisorn Jedpiyawongse,
Marcello Ceppi,
Suleeporn Sangrajrang,
Sara Piro,
Paolo Boffetta
Publication year - 2009
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0900907
Subject(s) - malondialdehyde , lipid peroxidation , dna adduct , deoxyguanosine , environmental health , petrochemical , oxidative stress , chemistry , air pollution , environmental chemistry , toxicology , carcinogen , medicine , biochemistry , biology , organic chemistry
Humans living near industrial point emissions can experience high levels of exposures to air pollutants. Map Ta Phut Industrial Estate in Thailand is the location of the largest steel, oil refinery, and petrochemical factory complexes in Southeast Asia. Air pollution is an important source of oxidative stress and reactive oxygen species, which interact with DNA and lipids, leading to oxidative damage and lipid peroxidation, respectively.
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