Transcriptional Biomarkers of Steroidogenesis and Trophoblast Differentiation in the Placenta in Relation to Prenatal Phthalate Exposure | Zendy

Jennifer J. Adibi | Zendy; Robin M. Whyatt | Zendy; Russ Hauser | Zendy; Hari K. Bhat | Zendy; Barbara J. Davis | Zendy; Antonia M. Calafat | Zendy; Lori Hoepner | Zendy; Frederica P. Perera | Zendy; Deliang Tang | Zendy; Paige L. Williams | Zendy

Open Access

Transcriptional Biomarkers of Steroidogenesis and Trophoblast Differentiation in the Placenta in Relation to Prenatal Phthalate Exposure

Author(s) -

Jennifer J. Adibi,

Robin M. Whyatt,

Russ Hauser,

Hari K. Bhat,

Barbara J. Davis,

Antonia M. Calafat,

Lori Hoepner,

Frederica P. Perera,

Deliang Tang,

Paige L. Williams

Publication year - 2009

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.0900788

Subject(s) - phthalate , trophoblast , placenta , biology , aromatase , endocrinology , cholesterol side chain cleavage enzyme , sexual differentiation , aryl hydrocarbon receptor , medicine , andrology , gene , cytochrome p450 , fetus , genetics , transcription factor , chemistry , pregnancy , organic chemistry , cancer , metabolism , breast cancer

Phthalates can alter steroidogenesis and peroxisome proliferator-activated receptor gamma (PPARgamma)mediated transcription in rodent tissues. The placenta offers a rich source of biomarkers to study these relationships in humans.

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