Atrazine Binds to the Growth Hormone–Releasing Hormone Receptor and Affects Growth Hormone Gene Expression | Zendy

Walid D. Fakhouri | Zendy; Joseph L. Nuñez | Zendy; Frances Trail | Zendy

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Atrazine Binds to the Growth Hormone–Releasing Hormone Receptor and Affects Growth Hormone Gene Expression

Author(s) -

Walid D. Fakhouri,

Joseph L. Nuñez,

Frances Trail

Publication year - 2010

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.0900738

Subject(s) - atrazine , growth hormone , hormone receptor , growth hormone receptor , hormone , gene expression , endocrinology , receptor , medicine , biology , growth hormone releasing hormone receptor , chemistry , gene , biochemistry , genetics , ecology , pesticide , cancer , breast cancer

Atrazine (ATR), a commonly used herbicide in the United States, is widely distributed in water and soil because of its mobility through ecosystems and its persistence in the environment. ATR has been associated with defects in sexual development in animals, but studies on mammalian systems have failed to clearly identify a cellular target.

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