Genomewide Analysis of Aryl Hydrocarbon Receptor Binding Targets Reveals an Extensive Array of Gene Clusters that Control Morphogenetic and Developmental Programs | Zendy

Maureen A. Sartor | Zendy; Michaël Schnekenburger | Zendy; Jennifer Marlowe | Zendy; John F. Reichard | Zendy; Ying Wang | Zendy; Yunxia Fan | Zendy; Ci Ma | Zendy; Saikumar Karyala | Zendy; Danielle Halbleib | Zendy; Xiangdong Liu | Zendy; Mario Medvedovic | Zendy; Alvaro Puga | Zendy

Open Access

Genomewide Analysis of Aryl Hydrocarbon Receptor Binding Targets Reveals an Extensive Array of Gene Clusters that Control Morphogenetic and Developmental Programs

Author(s) -

Maureen A. Sartor,

Michaël Schnekenburger,

Jennifer Marlowe,

John F. Reichard,

Ying Wang,

Yunxia Fan,

Ci Ma,

Saikumar Karyala,

Danielle Halbleib,

Xiangdong Liu,

Mario Medvedovic,

Alvaro Puga

Publication year - 2009

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.0800485

Subject(s) - aryl hydrocarbon receptor , chromatin immunoprecipitation , transcription factor , biology , nuclear receptor , gene , kegg , regulation of gene expression , gene regulatory network , transcriptional regulation , promoter , gene expression , chromatin , genetics , aryl hydrocarbon receptor nuclear translocator , microbiology and biotechnology , transcriptome

The vertebrate aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates cellular responses to environmental polycyclic and halogenated compounds. The naive receptor is believed to reside in an inactive cytosolic complex that translocates to the nucleus and induces transcription of xenobiotic detoxification genes after activation by ligand.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research