Maternal Pregnancy Levels of Polychlorinated Biphenyls and Risk of Hypospadias and Cryptorchidism in Male Offspring | Zendy

Katherine A. McGlynn | Zendy; XuGuang Guo | Zendy; Barry I. Graubard | Zendy; John W. Brock | Zendy; Mark A. Klebanoff | Zendy; Matthew P. Longnecker | Zendy

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Maternal Pregnancy Levels of Polychlorinated Biphenyls and Risk of Hypospadias and Cryptorchidism in Male Offspring

Author(s) -

Katherine A. McGlynn,

XuGuang Guo,

Barry I. Graubard,

John W. Brock,

Mark A. Klebanoff,

Matthew P. Longnecker

Publication year - 2009

Publication title -

environmental health perspectives

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.257

H-Index - 282

eISSN - 1552-9924

pISSN - 0091-6765

DOI - 10.1289/ehp.0800389

Subject(s) - hypospadias , anogenital distance , odds ratio , in utero , offspring , confidence interval , congener , medicine , pregnancy , gynecology , gestation , obstetrics , physiology , endocrinology , fetus , biology , chemistry , surgery , environmental chemistry , genetics

The etiologies of the male urogenital anomalies cryptorchidism and hypospadias are poorly understood. It has been suggested, however, that in utero hormone levels may be related to risk. Endocrine-disrupting chemicals, including polychlorinated biphenyl (PCB) compounds, may alter hormone levels and thereby affect the fetus.

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