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Prenatal Exposure to Bisphenol A at Environmentally Relevant Doses Adversely Affects the Murine Female Reproductive Tract Later in Life
Author(s) -
Retha R. Newbold,
Wendy N. Jefferson,
Elizabeth PadillaBanks
Publication year - 2009
Publication title -
environmental health perspectives
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.257
H-Index - 282
eISSN - 1552-9924
pISSN - 0091-6765
DOI - 10.1289/ehp.0800045
Subject(s) - benzhydryl compounds , pregnancy , physiology , prenatal exposure , bisphenol a , biology , reproductive tract , medicine , gestation , toxicology , andrology , endocrinology , genetics , chemistry , organic chemistry , epoxy
Exposure to endocrine-disrupting chemicals during critical developmental periods causes adverse consequences later in life; an example is prenatal exposure to the pharmaceutical diethylstilbestrol (DES). Bisphenol A (BPA), an environmental estrogen used in the synthesis of plastics, is of concern because its chemical structure resembles that of DES, and it is a "high-volume production" chemical with widespread human exposure.

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