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C1q nephropathy- unity in diversity.
Author(s) -
Pavan Malleshappa
Publication year - 2013
Publication title -
pubmed
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.226
H-Index - 9
ISSN - 2345-2781
DOI - 10.12861/jrip.2013.37
Subject(s) - mesangium , immunofluorescence , nephropathy , medicine , pathology , glomerular mesangium , electron microscope , immunology , optics , diabetes mellitus , endocrinology , antibody , physics
Implication for health policy/practice/research/medical educationC1q nephropathy refers to a disorder in which C1q deposits are seen in mesangium on immunofluorescence microscopy and mesangial electron dense deposits on electron microscopy. The diagnosis of C1q nephropathy is based on demonstration of intense C1q (dominant or co-dominant) positivity, mainly in the mesangium on immunofluorescence microscopy. Electron dense deposits of C1q in C1q nephropathy are confirmatory of the diagnostic entity.

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