Genetic Polymorphisms of NFΚB1 - 94 del / ins ATTG , NFΚB1A 2758 A > G and SUMO rs237025 G > A in Psoriasis | Zendy

Abdullateef A. Alzolibani | Zendy; Ahmed Settin | Zendy; Ahmed Ali Ahmed | Zendy; Hisham Ismail | Zendy; Noor Elhefni | Zendy; Ahmad A. Al Robaee | Zendy

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Genetic Polymorphisms of NFΚB1 - 94 del / ins ATTG , NFΚB1A 2758 A > G and SUMO rs237025 G > A in Psoriasis

Author(s) -

Abdullateef A. Alzolibani,

Ahmed Settin,

Ahmed Ali Ahmed,

Hisham Ismail,

Noor Elhefni,

Ahmad A. Al Robaee

Publication year - 2015

Publication title -

international journal of health sciences

Language(s) - English

Resource type - Journals

eISSN - 1658-7774

pISSN - 1658-3639

DOI - 10.12816/0024680

Subject(s) - psoriasis , allele , genotype , nfkb1 , nf κb , gene , medicine , immunology , genetics , gastroenterology , biology , transcription factor , inflammation

Nuclear factor-κB (NF-κB) and small ubiquitin-like modifier (SUMO4) are key transcription factors involved in the regulation of immune responses and apoptosis. The aim of this study is to test for the association of NF-κB and SUMO gene polymorphisms with the susceptibility and severity of psoriasis among Saudi cases.

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