Effects of Cumin Extract on oxLDL , Paraoxanase 1 Activity , FBS, Total Cholesterol , Triglycerides , HDL-C , LDL-C , Apo A1 , and Apo B in in the Patients with Hypercholesterolemia | Zendy

Keihan Ghatreh Samani | Zendy; Effat Farrokhi | Zendy

Open Access

Effects of Cumin Extract on oxLDL , Paraoxanase 1 Activity , FBS, Total Cholesterol , Triglycerides , HDL-C , LDL-C , Apo A1 , and Apo B in in the Patients with Hypercholesterolemia

Author(s) -

Keihan Ghatreh Samani,

Effat Farrokhi

Publication year - 2014

Publication title -

international journal of health sciences

Language(s) - English

Resource type - Journals

eISSN - 1658-7774

pISSN - 1658-3639

DOI - 10.12816/0006070

Subject(s) - apolipoprotein b , pon1 , chemistry , antioxidant , cholesterol , low density lipoprotein , high density lipoprotein , arylesterase , lipoprotein , apolipoprotein a1 , paraoxonase , food science , medicine , endocrinology , biochemistry , enzyme , genotype , gene

Paraoxanase 1 (PON1) plays a protective role against the oxidative modification of plasma lipoproteins and hydrolyzes lipid peroxides in human atherosclerotic lesions. Cumin is the dried seed of the herb Cuminumcyminum that is known as Zeera in Iran. Cumin seeds contain flavonoids which are now generally recognized to have antioxidant activity and improve the antioxidant system. So, they possibly modify PON1 activity and oxidized low density lipoprotein (oxLDL) level. The present study was aimed to evaluate the effects of cumin extract supplementation on oxLDL, paraoxanase 1 activity, FBS, total cholesterol, triglycerides, High density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), apolipoprotein A1 (Apo A1), and apolipoprotein B (Apo B)in the patients with hypercholesterolemia.

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