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Effect of Transforming Growth Factor Beta 1 on Wound Healing in Induced Diabetic Rats
Author(s) -
Hanaa El Gazaerly,
Dorria M Elbardisey,
Heba M Eltokhy,
Doaa Teaama
Publication year - 2013
Publication title -
international journal of health sciences
Language(s) - English
Resource type - Journals
eISSN - 1658-7774
pISSN - 1658-3639
DOI - 10.12816/0006040
Subject(s) - wound healing , granulation tissue , medicine , h&e stain , diabetes mellitus , transforming growth factor , extracellular matrix , staining , streptozotocin , inflammation , endocrinology , surgery , pathology , chemistry , biochemistry
Delayed wound healing is one of the complications of diabetes mellitus, exhibited by profound inflammation and decreased granulation tissues. The current study was carried out to evaluate wound healing in both normal and diabetic rats. In addition, it evaluated the potential protective effect of transforming growth factor β1 (TGF β1), that has the broadest spectrum of actions, affecting all cell types that are involved in all stages of wound healing to accelerate wound healing in normal & diabetic rats.

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