Update on TNF Inhibitors
Author(s) -
Francisco A. Kerdel
Publication year - 2016
Publication title -
seminars in cutaneous medicine and surgery
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.66
H-Index - 64
eISSN - 1558-0768
pISSN - 1085-5629
DOI - 10.12788/j.sder.2016.019
Subject(s) - medicine , etanercept , tumor necrosis factor alpha , psoriasis , tumor necrosis factor α , adalimumab , intensive care medicine , infliximab , pharmacology , dermatology
The introduction of tumor necrosis factor (TNF)-α inhibitors dramatically improved the management of psoriasis. Some newer or investigational biologics with different mechanisms of action have demonstrated noninferiority or superiority to etanercept, the first self-injectable anti-TNF-α agent to become available in the United States. Nonetheless, TNF-α inhibitors are likely to remain a mainstay of therapy for many years.
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