The role of S100B protein as a potential marker in affective disorders | Zendy

Aleksandra RajewskaRager | Zendy; Magdalena Pawlaczyk | Zendy

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The role of S100B protein as a potential marker in affective disorders

Author(s) -

Aleksandra RajewskaRager,

Magdalena Pawlaczyk

Publication year - 2016

Publication title -

psychiatria polska

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.414

H-Index - 22

eISSN - 2391-5854

pISSN - 0033-2674

DOI - 10.12740/pp/62393

Subject(s) - mania , mood disorders , bipolar disorder , depression (economics) , population , medicine , psychiatry , mood , psychology , clinical psychology , anxiety , environmental health , economics , macroeconomics

Both recurrent depressive disorders and affective bipolar disorders are characterized by the changes in glial tissue. S100B protein is a calcium-binding molecule, mainly secreted by glial cells, which, depending on its concentration, has a trophic or toxic effect on neuronal cells. In the recent years, due to the postulated glial hypothesis of affective disorders and the ideas concerning brain neuroplasticity, there has been a growing interest in S100B protein and its role in affective disorders.

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